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PGT-M: Preimplantation Genetic Testing for Monogenic Disorders in Bangalore

At Momsoon IVF, We provide advanced PGT-M screening to help identify healthy embryos and reduce the risk of inherited genetic disorders.
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What is PGT-M?

PGT-M refers to preimplantation genetic testing for monogenic disorders. It is a unique test performed on IVF embryos to detect single-gene problems that can lead to inherited disorders. The primary goal of this test is to help parents identify and select healthy embryos before getting pregnant.
Couples who do this decrease their chances of passing on a genetic problem to their child. The test is safe and accurate, helping families to make better decisions about their fertility journey.

Words to know:

Monogenic disorder: It is a condition caused by a single change in a gene.

Single-gene testing: It involves checking one gene to see if it has an issue.

Embryo biopsy: Taking a few cells from an embryo for laboratory testing.

Genetic mutation: A small change in DNA that might cause sickness

Health embryo selection: selecting embryos without dangerous genes for transfer.

How PGT-M Works

The PGT-M process takes place along with the IVF treatment. It helps identify embryos that are free from single-gene disorders before pregnancy begins. The test involves a few simple but important steps carried out with great care by fertility experts.

Here is how it works step by step:

1. IVF procedure and egg retrieval

The process starts with IVF, where eggs are collected from the woman and fertilized with sperm in the laboratory. This creates several embryos for testing.
After a few days of growth, a small number of cells are carefully removed from each embryo. This step is safe and does not harm the embryo.
Cells taken from the embryo are tested in a lab to look for specific gene changes that may lead to genetic disorders. The lab finds which embryos have that defective gene and which don’t.
Only embryos without genetic disorders are chosen for transfer into the uterus, increasing the chance of a successful pregnancy.
Through these steps, monogenic disorder testing helps couples make informed choices and increases their chance of having a healthy baby free of single-gene disorders.

Who Should Consider PGT-M?

PGT-M is suggested mainly for couples with a family history of genetic disorders or who carry a single gene change. It decreases their chance that they get these conditions onto their babies. This exam is important for parents who wish to make safe and informed decisions about their IVF treatment.

You and your partner have a known family history of inherited disorders.

You are a carrier of a genetic mutation.

You already have a child with a genetic disease.

You want to prevent single-gene conditions such as cystic fibrosis, thalassemia, Huntington’s disease, or sickle cell anaemia.

Benefits of PGT-M

PGT-M helps in recognising healthy embryos before pregnancy, decreasing the risk of genetic diseases being transmitted to future children. It increases couples’ confidence, emotional comfort, and control over their family planning decisions.

Main benefits include:

Higher chance of a healthy pregnancy and baby.

Reduced risk of inherited genetic disorders.

Accurate and confident embryo selection.

Fewer issues and emotional stress throughout pregnancy.

Higher IVF success rates and better outcomes for families.

PGT-M allows couples with a history of genetic problems to create a healthy family while protecting future generations from inheriting single-gene disorders.

PGT-M vs Other Genetic Tests (PGT-A / PGD)

There are a variety of genetic tests done during IVF, each with a specific purpose. While they all help in the selection of healthy embryos, their focus and uses differ. PGT-M is specially used for single-gene embryo testing, making it perfect for families with known inherited conditions who want to have a healthy child.
Test type
Purpose
Used for
PGT- M
Detects single gene abnormalities that cause hereditary conditions.
Detects single gene abnormalities that cause hereditary conditions. Couples with a known family history of genetic disorders like cystic fibrosis or Huntington’s disease.
PGT-A
Checks if embryos have the correct number of chromosomes.
Couples with repeated IVF failures or miscarriages.
PGD
A broad term for genetic testing of embryos before
General genetic diagnosis.

Why Momsoon IVF Stands Out for PGT-M Testing

Momsoon IVF is one of the trusted fertility centres in Bangalore for PGT-M testing. The clinic combines advanced IVF technology with expert care to help couples achieve a healthy pregnancy. Every step is guided by skilled specialists who make the process simple, clear, and supportive for families. At Momsoon, both IVF and genetic testing are done using the latest methods to give accurate results and peace of mind to patients. We focus on care, trust, and honest communication throughout the journey.

What makes Momsoon IVF special

Advanced IVF and genetic testing infrastructure.

Highly experienced specialists and embryologists.

Strong collaborations with leading genetic diagnostic centers.

Personalized care and one-on-one counseling for every couple.

A reputation built on transparency and trust.

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