What is Non-Invasive Pre-Implantation Genetic Testing (niPGT-A)?

Non-Invasive Pre-Implantation Genetic Testing (niPGT-A) is a safe and gentle method used during IVF to check how healthy an embryo is before it is transferred. The embryo is never touched or harmed during this test. Instead, specialists look at small pieces of cell-free DNA (cfDNA) that the embryo naturally releases into the liquid in which it grows. This DNA helps reveal if there are any chromosomal or genetic problems that could lead to miscarriage, failed implantation, or inherited diseases. Since no cells are taken from the embryo, the process is completely harmless. Many couples choose niPGT-A because it helps them understand their embryo’s health better and raises their chances of a healthy pregnancy.

How Does Non-Invasive Pre-Implantation Genetic Testing Work?

A Step-by-Step Overview of the niPGT-A Process

1. Embryo Culture

Embryos are carefully grown in a special liquid inside the IVF lab for a few days. This is a safe environment that helps them develop naturally while releasing a small amount of DNA.
After the embryos have grown, the liquid in which they developed is gently collected. This liquid contains the embryo’s cell-free DNA (cfDNA), which is used for testing.
Experts separate and collect the DNA from the culture liquid. This DNA carries important information about the embryo’s genetic and chromosomal health, which helps guide further analysis.
The extracted DNA is then analysed using advanced tools to study its structure. This helps identify any chromosomal problems that could affect embryo growth or pregnancy for the couple.
After testing, healthy embryos without genetic issues are chosen for transfer. This step increases the chances of successful implantation and a healthy pregnancy.

Advantages of Non-Invasive Pre-Implantation Genetic Testing

No Risk to Embryos

The test is completely safe because the embryo is not touched or harmed. It studies the DNA naturally released into the liquid where the embryo grows.

Improved IVF Success Rates

By helping select the healthiest embryos, niPGT-A increases the chances of a successful pregnancy and reduces the need for more IVF cycles.

Reduced Miscarriage Risk

Since embryos with genetic problems can be identified early, the chances of miscarriage are lower, giving couples a safer and more positive IVF experience.

Ethically Preferred

Many couples prefer niPGT-A because it does not harm the embryo. It gives a natural and respectful way to understand embryo health before transfer.

Compatible with Blastocyst Culture

The test works best with embryos grown to the blastocyst stage, providing clear and exact genetic information without affecting embryo growth.

Why Choose Non-Invasive Pre-Implantation Genetic Testing for Your IVF Journey?

Safe and gentle for the Embryo

No need to touch or remove Embryo cells

Finds genetic problems early and clearly

Helps pick the healthiest Embryos for transfer

Lowers the risk of miscarriage or failed implantation

Increases IVF success and pregnancy rates

Good for women of all ages and IVF cases

Done with modern lab tools and expert care

A natural and kind way to check embryos

Who Should Consider niPGT-A?

niPGT-A is useful for couples who want to increase their IVF success while keeping their embryos safe. It is especially helpful for those with a higher risk of genetic problems.

Women above 35 often face a higher chance of chromosomal errors. niPGT-A helps find healthy embryos, increasing the chances of a successful pregnancy.

Women over 35

Couples who have faced more miscarriages or IVF failures, niPGT-A helps find strong and healthy embryos that are more likely to implant successfully.

Couples with recurrent miscarriages or failed IVF cycles

Those who want a completely safe and non-invasive testing method can select niPGT-A, as it does not harm or touch the embryo during testing.

Patients seeking safer alternatives

Couples who carry genetic conditions can benefit from niPGT-A, as it helps decrease the risk of passing these disorders to their child.

Those with known genetic disorders

Couples who only wish to transfer one embryo, niPGT-A helps in choosing the strongest, healthiest one, increasing the chances of pregnancy and safe delivery.

Couples considering elective single embryo transfer

Comparing niPGT and Traditional PGT

Feature
niPGT-A
Traditional PGT
Method
Uses DNA from the embryo fluid
Takes cells from the embryo
Risk
No harm to the embryo
Small risk of damage
Accuracy

Good results

Very accurate
Process
Simple and gentle
Complex and skill-based
Use
Safer for most IVF cases
Older or high-risk patients

Cost

More affordable
More expensive
Time Cost
Quick allows fresh transfer.
Slower, needs freezing

How Accurate Is niPGT-A? Success Rates and Results You Can Trust

Recent studies show that niPGT-A is a very reliable way to choose healthy embryos during IVF. Medical reports say that niPGT-A is about 90% accurate, and its results keep getting better with new lab technology. Many IVF clinics now see higher pregnancy rates and better embryo selection using niPGT-A. The test helps doctors pick healthy embryos early, so couples need fewer IVF cycles and have a higher chance of a successful pregnancy.

Why Choose Momsoon IVF for niPGT

Pioneers in Advanced Genetic Testing

Among the first clinics in Bangalore to offer cutting-edge non-invasive PGT with proven accuracy and safety.

Expert Embryologists & Genetic Specialists

A highly experienced team ensuring precise embryo screening and reliable genetic analysis.

No Risk to Embryos

Uses cell-free DNA technology, making the process completely non-invasive and safe for embryo development.

Higher IVF Success Rates

Improved embryo selection increases implantation success and reduces the risk of genetic abnormalities.

Personalized Fertility Care

Tailored treatment plans designed to meet each couple’s unique fertility and genetic needs.

Ethical & Transparent Practices

Clear communication, detailed reports, and patient-first ethics at every stage.

Schedule Your Consultation

Book a consultation with our fertility experts today to learn how niPGT-A can enhance your IVF success. Our specialists will guide you through every step of the process, from testing to embryo selection.

Success Stories from Our Happy Parents

We are forever grateful to Momsoon Fertility IVF Center. After years of trying, their expert infertility treatment helped us welcome our baby. The doctors and staff were very supportive throughout the IVF journey. Truly the best fertility clinic in the city.

Shashikala & Vinoothan

Momsoon IVF Center gave us hope when we had lost all. The care and personal attention made all the difference. If anyone is looking for the best IVF doctor and a trusted fertility clinic, this is the place to go.

Kavitha & Ramesh

Highly recommend Momsoon Fertility Center for anyone facing difficulty conceiving. The clinic has advanced IVF treatment and experienced doctors. We are now proud parents thanks to them.

Chaya & Aravind

I can't thank Momsoon IVF Clinic enough. Their expert team made my dream come true. The process was explained well, and the treatment felt personal and caring. One of the most trusted fertility clinics in town.

Padmavathi & Ganesha

The team at Momsoon Fertility Center is extremely supportive and knowledgeable. They guided us patiently through every step of our IVF treatment. We always felt informed and confident. Definitely one of the best IVF centers.

Shanthamma & Muniraj

What stood out at Momsoon Fertility IVF Clinic was the clean and peaceful environment. It gave us so much comfort during a stressful time. Great facilities and experienced staff made everything smooth.

Jyothirmayee & Venkateswarlu

After trying for over 5 years, we finally got our positive result at Momsoon Fertility Center. Their infertility treatment is very advanced and the emotional support they offer is unmatched.

Lakshmi & Shivakumar

Success on the first attempt! We feel so lucky to have found Momsoon IVF Center. From consultation to embryo transfer, everything was handled professionally. Best IVF center in India in our opinion.

Sumanjali & Ashok

Every nurse, staff member, and doctor at Momsoon IVF Clinic treated us like family. We always felt welcomed and well informed. For anyone looking for compassionate infertility treatment, this is the place.

Sudha & Sritharan

Momsoon Fertility Center uses the latest IVF techniques and has an amazing lab setup. We were very impressed with how transparent and scientific everything was. We highly recommend this fertility clinic.

Roopa & Nagabhushan

Frequently Asked Questions

What is the difference between PGT-A and niPGT-A?
PGT-A tests a few cells taken directly from the embryo, while niPGT-A uses the DNA released into the fluid around the embryo. niPGT-A is gentle and doesn’t touch the embryo, making it a safer option.
Yes, niPGT-A is completely safe. It doesn’t involve removing cells from the embryo, so there’s no risk of harm or damage during testing.
Studies show that niPGT-A can be up to 90% accurate, and with advanced lab methods, its results are becoming even more reliable
The process is quick and usually fits within the normal IVF cycle. It doesn’t delay embryo transfer.
Results are usually available soon after testing, depending on the clinic’s laboratory process.
niPGT-A is safe, stress-free for the embryo, and helps select healthy embryos early. This increases the chances of pregnancy and reduces the number of IVF cycles needed.

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